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The main difference between androgenic and anabolic is that androgenic steroids generate male sex hormone-related activity whereas anabolic steroids increase both muscle mass and the bone massof the body. Although there are clear physiological effects of androgenic steroids on the body during normal body growth, such as bone accretion, the effects on skeletal muscle were less well studied. Thus, the aims of this study were to investigate the biochemical events accompanying an increase in body mass in a rat model of muscle hypertrophy induced by anabolic androgenic steroids and to determine the hormonal effects of these steroids and to clarify the effects of the steroids on the protein synthetic response in rat aorta. METHODS Animals. Wistar rats were provided with ad libitum food and environmental enrichment, but had been treated with an androgen receptor-blocking drug (Raltefosin, 0.1 mg/kg/day) to suppress androgen production before the experiment. After a 5-week period of acclimation, this drug was switched off (5 mg/kg/day) and rats were then divided into three groups: (1) rats that received vehicle alone, or (2) a 3 mg/kg daily dose of testosterone enanthate and (3) mice treated with anandamide (1 and 10 mg/kg, 2 and 6 hr thereafter). The same dosage and the same conditions were applied to the third group of animals. The doses of androgens were chosen within the framework of the A1/A2 receptor agonist (Estradiol) and androgen receptor antagonist (Fandrolone acetate, 10 mg/kg), which are the most widely used drugs in the treatment of hirsutism and male pattern hair loss. The third group of animals was injected with androgen receptor blockade (anandamide, 10 mg/kg) 30 min before the injection of the vehicle or testosterone enanthate. The vehicle and testosterone enanthate were not used during this drug administration study. This study was approved by the institutional animal care department. Testosterone Enanthate. The testosterone enanthate had been created using the natural source (i.e. human body) and its activity was confirmed by pharmacological assays. The dose of anandamide was 1.5 mg/kg/day (0.1 mg/kg/day in rats, but higher doses (1 and 10 mg/ kg) may be effective for the treatment of hirsutism). Testosterone Enanthate (3 mg/kg/day) was administered by gavage on day 5 of the acclimation period. The testosterone enanthate was dissolved in ethanol Related Article:

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Primobolan 50 mg, buy steroids in greece

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